This. Shopping and dining in central. Seneca Niagara Casino & Hotel is a casino in Niagara Falls, New York, United States. Nestled in the heart of Niagara Falls, New York, Seneca Niagara Resort & Casino offers an unbeatable location in the vibrant Niagara Falls City Center. With more than slot machines, almost table games, Seneca Niagara Casino offers some of the best thrills near Niagara Falls, USA. It was built by the Seneca Nation to compete with Casino Niagara and. Now £ on Tripadvisor: Seneca Niagara Resort & Casino, Niagara Falls. Seneca Niagara Resort & Casino in Niagara Falls, NY USA boasts a AAA Four-Diamond hotel with rooms, exciting full-service casino & top-tier amenities. Seneca Niagara Resort & Casino is conveniently located in Niagara Falls, NY, a vacation destination with plenty of sights to see and activities for everyone. . See traveller reviews, candid photos, and great deals for Seneca Niagara. Seneca Niagara Resort & Casino is a full-amenity resort located in picturesque Niagara Falls, New York. This AAA Four Diamond rated hotel features Seneca Niagara Resort & Casino is located in Niagara Falls NY and is close to nearby sightseeing spots, such as Maid of the Mist, Niagara Falls State Park. Seneca Niagara Resort & Casino features a casino and puts you a short five-minute drive from Fallsview Indoor Waterpark. You can visit the spa to be pampered. This New York hotel is less than 1 km from Niagara Falls and boasts an on-site casino, spa, and various dining options.